8,8'-DIAPOCAROTENEDIOIC ACID
- Product Name
- 8,8'-DIAPOCAROTENEDIOIC ACID
- CAS No.
- 27876-94-4
- Chemical Name
- 8,8'-DIAPOCAROTENEDIOIC ACID
- Synonyms
- CROCETIN;TRANS-CROCETIN;NSC407300;a-Crocetin;roceic acid;Alpha-Crocetin;Crocetin (6CI);Stable crocetin;trans-Crocetine;CROCETIN, TRANS-
- CBNumber
- CB5780370
- Molecular Formula
- C20H24O4
- Formula Weight
- 328.4
- MOL File
- 27876-94-4.mol
8,8'-DIAPOCAROTENEDIOIC ACID Property
- Melting point:
- 285°
- Boiling point:
- 386.14°C (rough estimate)
- Density
- 1.0786 (rough estimate)
- refractive index
- 1.4434 (estimate)
- FEMA
- 2998 | SAFFRON (CROCUS SATIVUS L.)
- storage temp.
- Inert atmosphere,Store in freezer, under -20°C
- solubility
- DMSO (Slightly, Heated), Methanol (Slightly)
- form
- Solid
- pka
- 4.39±0.19(Predicted)
- color
- Red to Very Dark Red
- Stability:
- Light Sensitive
- LogP
- 4.312 (est)
Safety
- HS Code
- 29171900
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H317May cause an allergic skin reaction
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352IF ON SKIN: wash with plenty of soap and water.
N-Bromosuccinimide Price
- Product number
- SML3255
- Product name
- Crocetin
- Purity
- ≥98% (HPLC)
- Packaging
- 5MG
- Price
- $8.8
- Updated
- 2024/03/01
- Product number
- SML3255
- Product name
- Crocetin
- Purity
- ≥98% (HPLC)
- Packaging
- 25MG
- Price
- $43.8
- Updated
- 2024/03/01
- Product number
- PHL86280
- Product name
- Crocetin
- Purity
- phyproof? Reference Substance
- Packaging
- 10MG
- Price
- $249
- Updated
- 2024/03/01
- Product number
- 24217
- Product name
- Transcrocetin
- Purity
- ≥98%
- Packaging
- 5mg
- Price
- $81
- Updated
- 2024/03/01
- Product number
- 24217
- Product name
- Transcrocetin
- Purity
- ≥98%
- Packaging
- 10mg
- Price
- $152
- Updated
- 2024/03/01
8,8'-DIAPOCAROTENEDIOIC ACID Chemical Properties,Usage,Production
Chemical Properties
Red, rhomboid crystals.Soluble in pyridine and dilute sodium hydroxide; slightly soluble in water and organic solvents. Combustible.
Uses
Experimental treatment of arteriosclerosis by increasing oxygen diffusion through arterial walls, thus decreasing buildup of cholesterol.
Uses
Crocetin is a carotenoid derived from saffron, and is shown to have anticancer effects in both human adenocarcinoma gastric cancer cells and rat model of gastric cancer.
Definition
ChEBI: A 20-carbon dicarboxylic acid which is a diterpenoid and natural carotenoid. Found in the crocus flower, it has been administered as an anti-fatigue dietary supplement.
Anticancer Research
It is a natural apocarotenoid dicarboxylic acid obtained from saffron, and saffron isa spice from the flower of the Saffron crocus and present in the dry stigmas of theplant Crocus sativus which can be used as a food colorant. It is reported to be anovel anticancer agent against hepatocellular carcinoma, pancreatic cancer, lungcancer, skin carcinoma, breast cancer, and colorectal cancer. It inhibits the nucleicacid synthesis, enhances antioxidant system, induces apoptosis, hinders growthfactor signaling pathways, and thus affects the growth of cancer cells. It showseffects in the reduction of LPS-induced nitric oxide release; in the reduction ofproduced IL-1β, TNF-α, and intracellular ROS; in the activation of NF-κB; and inthe blockade of LPS (Wang et al. 2012; Gutheil et al. 2012).
target
COX | NO
8,8'-DIAPOCAROTENEDIOIC ACID Preparation Products And Raw materials
Raw materials
Preparation Products
8,8'-DIAPOCAROTENEDIOIC ACID Suppliers
View Lastest Price from 8,8'-DIAPOCAROTENEDIOIC ACID manufacturers
- Product
- Crocetin 27876-94-4
- Price
- US $0.00/kg
- Min. Order
- 1kg
- Purity
- 75% 98%
- Supply Ability
- 1000 kg
- Release date
- 2024-04-26
- Product
- Croceic acid 27876-94-4
- Price
- US $0.00/mg
- Min. Order
- 20mg
- Purity
- ≥98%(HPLC)
- Supply Ability
- 10 g
- Release date
- 2020-05-07
- Product
- 8,8'-DIAPOCAROTENEDIOIC ACID 27876-94-4
- Price
- US $1.00/KG
- Min. Order
- 1G
- Purity
- 98%
- Supply Ability
- 100KG
- Release date
- 2018-08-15